Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Autophagy is essential for cellular homeostasis and when deregulated this survival mechanism has been associated with disease development. Inhibition of autophagy initiation by inhibiting the kinase ULK1 has been proposed as a potential cancer therapy. While inhibitors and crystal structures of ULK1 have been reported, little is known about the oth...
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Full title
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
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TN_cdi_proquest_journals_2180197802
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2180197802
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E-ISSN
2692-8205
DOI
10.1101/550111
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https://www.proquest.com/docview/2180197802?pq-origsite=primo&accountid=13902
