Loss of TET proteins in regulatory T cells unleashes effector function
Loss of TET proteins in regulatory T cells unleashes effector function
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
TET enzymes oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and other oxidized methylcytosines, mediating DNA demethylation and serving as new epigenetic marks. Here we examine the role of TET proteins in Foxp3+ regulatory T (Treg) cells, a distinct lineage of CD4+ T cells that prevent autoimmunity and maintain immune homeostasis....
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Full title
Loss of TET proteins in regulatory T cells unleashes effector function
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TN_cdi_proquest_journals_2181663721
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2181663721
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E-ISSN
2692-8205
DOI
10.1101/551093
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https://www.proquest.com/docview/2181663721?pq-origsite=primo&accountid=13902
