Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling
Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Microglia rapidly respond to changes in neural activity and inflammation to regulate synaptic connectivity. The extracellular signals, particularly neuron-derived molecules, that drive these microglial functions at synapses remains a key open question. Here, whisker lesioning, known to dampen cortical activity, induces microglia-mediated synapse el...
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Full title
Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling
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TN_cdi_proquest_journals_2181666341
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2181666341
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E-ISSN
2692-8205
DOI
10.1101/551697
How to access this item
https://www.proquest.com/docview/2181666341?pq-origsite=primo&accountid=13902
