The protective effect of hydrogen sulfide on intestinal ischemia-reperfusion injury in rats / 硫化氢对大鼠...
The protective effect of hydrogen sulfide on intestinal ischemia-reperfusion injury in rats / 硫化氢对大鼠肠缺血再灌注损伤的保护作用
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Full title
The protective effect of hydrogen sulfide on intestinal ischemia-reperfusion injury in rats / 硫化氢对大鼠肠缺血再灌注损伤的保护作用
Publisher
Xi'an: Xi'an Jiaotong University
Journal title
Xi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban, 2007-01 (6), p.668
Language
Chinese
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Publication information
Publisher
Xi'an: Xi'an Jiaotong University
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More information
Scope and Contents
Contents
目的 研究硫化氢(H2S)对肠缺血再灌注损伤(I/R)的保护作用,为临床治疗I/R提供新的可能途径.方法 以硫化氢钠(NaHS)为H2S的供体,将40只SD大鼠随机分为假手术组、I/R模型组、川芎嗪对照组、NaHS(7μmol/kg和14μmol/kg)组,每组8只.检测各组血清和小肠组织的超氧化物歧化酶(SOD)、丙二醛(MDA)和谷胱甘肽过氧化物酶(GSH-Px)的含量,观察小肠黏膜病理组织学变化.结果 H2S能显著降低I/R大鼠血清和小肠组织MDA水平,提高SOD、GSH-Px水平;小肠黏膜和腺体的损伤较I/R模型组明显减轻.结论 H2S对I/R引起的肠黏膜损伤有保护作用.
Alternative Titles
Full title
The protective effect of hydrogen sulfide on intestinal ischemia-reperfusion injury in rats / 硫化氢对大鼠肠缺血再灌注损伤的保护作用
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TN_cdi_proquest_journals_2182398776
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2182398776
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ISSN
1671-8259
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