Expression and significance of chemokine SDF-1 and its receptor CXCR4 in human epithelial ovarian tu...
Expression and significance of chemokine SDF-1 and its receptor CXCR4 in human epithelial ovarian tumours / SDF-1及其受体CXCR4在上皮性卵巢肿瘤中的表达及意义
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Xi'an: Xi'an Jiaotong University
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Chinese
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Xi'an: Xi'an Jiaotong University
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目的 探讨趋化因子SDF-1及其受体CXCR4在上皮性卵巢肿瘤组织中的表达及临床意义.方法 应用免疫组织化学SP法检测10例正常卵巢上皮组织,21例卵巢良性肿瘤、19例交界性卵巢肿瘤、30例卵巢癌原发灶和11例相应盆腔腹膜转移灶组织中SDF-1和CXCR4蛋白表达情况.结果 正常卵巢上皮组织SDF-1和CXCR4表达阴性,卵巢良性肿瘤低表达SDF-1(9.52%),CXCR4表达阴性,与正常卵巢及良性卵巢肿瘤相比,交界性卵巢肿瘤、卵巢癌原发灶及转移灶表达较高水平的SDF-1与CXCR4(63.16%、93.33%、90.91%;47.37%、63.33%、63.64%).交界性卵巢肿瘤中SDF-1和CXCR4表达无显著相关性(P=0.460);而卵巢癌原发灶中SDF-1和CXCR4表达呈正相...
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Full title
Expression and significance of chemokine SDF-1 and its receptor CXCR4 in human epithelial ovarian tumours / SDF-1及其受体CXCR4在上皮性卵巢肿瘤中的表达及意义
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TN_cdi_proquest_journals_2182398792
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2182398792
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1671-8259
