A clinical study on lamivudine treatment for decompensated cirrhosis due to hepatitis B / 拉米夫定治疗失代偿期...
A clinical study on lamivudine treatment for decompensated cirrhosis due to hepatitis B / 拉米夫定治疗失代偿期乙肝肝硬化的临床研究
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Xi'an: Xi'an Jiaotong University
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Chinese
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Xi'an: Xi'an Jiaotong University
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目的 探讨失代偿期乙肝肝硬化患者应用拉米夫定(LVD)治疗的临床效果及对病程进展的影响.方法 108例失代偿期乙肝肝硬化患者随机分成治疗组(58例)和对照组(50例).治疗组服用LVD 100 mg/d,同时给予常规综合治疗.对照组仅给予常规综合治疗,随访时间为(28±3)个月.结果 治疗组和对照组死亡率分别为6.9%和14.0%(P＜0.05),Child Pugh评分下降≥2分的患者分别为89.2%和62.4%(P＜0.05).肝癌发生率分别为3.4%和4.0%(P＞0.05).治疗组在降低血清胆红素和转氨酶、升高血清白蛋白水平、降低Child Pugh评分、改善肝功能方面均明显优于对照组.治疗后HBeAg和HBV-DNA转阴率以及HBeAg血清转换率明显高于对照组(P＜0.05).治疗...
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Full title
A clinical study on lamivudine treatment for decompensated cirrhosis due to hepatitis B / 拉米夫定治疗失代偿期乙肝肝硬化的临床研究
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TN_cdi_proquest_journals_2182406463
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2182406463
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1671-8259
