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Activation of GABAB receptors reverses spontaneous gating deficits in juvenile DBA/2J mice

Activation of GABAB receptors reverses spontaneous gating deficits in juvenile DBA/2J mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_218962797

Activation of GABAB receptors reverses spontaneous gating deficits in juvenile DBA/2J mice

About this item

Full title

Activation of GABAB receptors reverses spontaneous gating deficits in juvenile DBA/2J mice

Publisher

Heidelberg: Springer Nature B.V

Journal title

Psychopharmacology, 2007-10, Vol.194 (3), p.361-369

Language

English

Formats

Publication information

Publisher

Heidelberg: Springer Nature B.V

More information

Scope and Contents

Contents

Rationale: Gamma-amino-butyric acid (GABA)B receptors play a key role in the pathophysiology of psychotic disorders. We previously reported that baclofen, the prototypical GABAB agonist, elicits antipsychotic-like effects in the rat paradigm of prepulse inhibition (PPI) of the startle, a highly validated animal model of schizophrenia. Objectives: W...

Alternative Titles

Full title

Activation of GABAB receptors reverses spontaneous gating deficits in juvenile DBA/2J mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_218962797

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_218962797

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-007-0845-5

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