RO4938581, a novel cognitive enhancer acting at GABAA [alpha]5 subunit-containing receptors
RO4938581, a novel cognitive enhancer acting at GABAA [alpha]5 subunit-containing receptors
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Publisher
Heidelberg: Springer Nature B.V
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Language
English
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Publisher
Heidelberg: Springer Nature B.V
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Contents
GABAA α5 subunit-containing receptors are primarily expressed in the hippocampus and their role in learning and memory has been demonstrated recently by both genetic and pharmacological approaches. The objective of the study is to evaluate the cognitive effects of a novel GABAA α5 receptor inverse agonist, RO4938581 in rats and monkeys. The in vitr...
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Full title
RO4938581, a novel cognitive enhancer acting at GABAA [alpha]5 subunit-containing receptors
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TN_cdi_proquest_journals_218965007
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_218965007
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ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-008-1357-7
