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Constitutive Siglec-1 expression by human dendritic cell precursors enables HIV-1 replication and tr...

Constitutive Siglec-1 expression by human dendritic cell precursors enables HIV-1 replication and tr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2191214138

Constitutive Siglec-1 expression by human dendritic cell precursors enables HIV-1 replication and transmission

About this item

Full title

Constitutive Siglec-1 expression by human dendritic cell precursors enables HIV-1 replication and transmission

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Human dendritic cell (DC) lineage has been recently unraveled by high dimensional mapping revealing the existence of a discrete new population of blood circulating DC precursor (pre-DC also referred to as AS DC). Among all blood DC subsets, only pre-DC highly express Siglec-1, a lectin-like receptor able to bind HIV-1. We show that pre-DC are uniqu...

Alternative Titles

Full title

Constitutive Siglec-1 expression by human dendritic cell precursors enables HIV-1 replication and transmission

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2191214138

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2191214138

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/578377