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A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combi...

A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2194118430

A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine

About this item

Full title

A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2019-03, Vol.120 (6), p.579-586

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
Capecitabine and eribulin are widely used as single agents in metastatic breast cancer (MBC) and have nonoverlapping toxicities.
Methods
In phase 1b (dose escalation), patients with advanced, treatment-refractory, solid tumours received eribulin mesilate intravenously in 21-day cycles according to schedule 1 (day 1) or schedule...

Alternative Titles

Full title

A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2194118430

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2194118430

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/s41416-018-0366-5

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