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Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2194963796

Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

About this item

Full title

Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Flow-activated transcription factor Krüppel-like factor 2 (KLF2) signaling is compromised in pulmonary arterial hypertension (PAH). We aimed to identify KLF2-induced endothelium-protective exosomal microRNAs of potential therapeutic significance. Eight exosomal microRNAs elevated by KLF2 but reduced in PAH were transfected into human pulmonary arte...

Alternative Titles

Full title

Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2194963796

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2194963796

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/583633