Beta-lactamase database (BLDB) - structure and function
Beta-lactamase database (BLDB) - structure and function
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Author / Creator
Publisher
England: Taylor & Francis
Journal title
Language
English
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Publisher
England: Taylor & Francis
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Scope and Contents
Contents
Beta-Lactamase Database (BLDB) is a comprehensive, manually curated public resource providing up-to-date structural and functional information focused on this superfamily of enzymes with a great impact on antibiotic resistance. All the enzymes reported and characterised in the literature are presented according to the class (A, B, C and D), family and subfamily to which they belong. All three-dimensional structures of β-lactamases present in the Protein Data Bank are also shown. The characterisation of representative mutants and hydrolytic profiles (kinetics) completes the picture and altogether these four elements constitute the essential foundation for a better understanding of the structure-function relationship within this enzymes family. BLDB can be queried using different protein- and nucleotide-based BLAST searches, which represents a key feature of particular importance in the context of the surveillance of the evolution of the antibiotic resistance. BLDB is available online at
http://bldb.eu
without any registration and supports all modern browsers....
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Full title
Beta-lactamase database (BLDB) - structure and function
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2195228368
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2195228368
Other Identifiers
ISSN
1475-6366,1475-6374
E-ISSN
1475-6374
DOI
10.1080/14756366.2017.1344235
