In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-ph...
In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria
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England: Taylor & Francis
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English
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England: Taylor & Francis
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Context: Malaria remains one of the prevalent infectious diseases worldwide. Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate reductoisomerase (PfDXR) plays a role in isoprenoid biosynthesis in the malaria parasite, making this parasite enzyme an attractive target for antimalarial drug design. Fosmidomycin is a promising DXR inhibitor, which sh...
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In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria
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TN_cdi_proquest_journals_2195295064
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2195295064
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ISSN
1388-0209,1744-5116
E-ISSN
1744-5116
DOI
10.1080/13880209.2016.1225778
