Poly(ADP-ribose) Accumulation and Enhancement of Postischemic Brain Damage in 110-kDa Poly(ADP-ribos...
Poly(ADP-ribose) Accumulation and Enhancement of Postischemic Brain Damage in 110-kDa Poly(ADP-ribose) Glycohydrolase Null Mice
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London, England: SAGE Publications
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Language
English
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London, England: SAGE Publications
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Poly(ADP-ribose) (PAR) is a polymer synthesized by poly(ADP-ribose) polymerases (PARPs) and metabolized into free adenosine diphosphate (ADP)-ribose units by poly(ADP-ribose) glycohydrolase (PARG). Perturbations in PAR synthesis have been shown to play a key role in brain disorders including postischemic brain damage. A single parg gene but two PAR...
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Full title
Poly(ADP-ribose) Accumulation and Enhancement of Postischemic Brain Damage in 110-kDa Poly(ADP-ribose) Glycohydrolase Null Mice
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TN_cdi_proquest_journals_219559370
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_219559370
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ISSN
0271-678X
E-ISSN
1559-7016
DOI
10.1038/sj.jcbfm.9600222
