Amplification of DNA damage-inducible transcript 3 (DDIT3) is associated with myxoid liposarcoma-lik...
Amplification of DNA damage-inducible transcript 3 (DDIT3) is associated with myxoid liposarcoma-like morphology and homologous lipoblastic differentiation in dedifferentiated liposarcoma
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Dedifferentiated liposarcoma is defined as progression of atypical lipomatous tumor/well-differentiated liposarcoma to a higher grade usually non-lipogenic sarcoma, with amplification of 12q13-15. This region contains several genes involved in liposarcoma pathogenesis, including
MDM2
,
CDK4
, and
DDIT3
. While the former two are t...
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Full title
Amplification of DNA damage-inducible transcript 3 (DDIT3) is associated with myxoid liposarcoma-like morphology and homologous lipoblastic differentiation in dedifferentiated liposarcoma
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TN_cdi_proquest_journals_2198554444
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2198554444
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ISSN
0893-3952
E-ISSN
1530-0285
DOI
10.1038/s41379-018-0171-y
