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Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the...

Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_219977313

Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study

About this item

Full title

Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study

Publisher

Chicago, IL: The University of Chicago Press

Journal title

Clinical infectious diseases, 2006-07, Vol.43 (1), p.99-102

Language

English

Formats

Publication information

Publisher

Chicago, IL: The University of Chicago Press

More information

Scope and Contents

Contents

Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle. In this prospective study, involving 260 abacavir-naive individuals (7.7% of whom were positive for HLA-B*5701), we confirm the usefulness of genetic risk stratif...

Alternative Titles

Full title

Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_219977313

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_219977313

Other Identifiers

ISSN

1058-4838

E-ISSN

1537-6591

DOI

10.1086/504874

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