Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the...
Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study
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Full title
Author / Creator
Rauch, A. , Nolan, D. , Martin, A. , McKinnon, E. , Almeida, C. and Mallal, Simon
Publisher
Chicago, IL: The University of Chicago Press
Journal title
Language
English
Formats
Publication information
Publisher
Chicago, IL: The University of Chicago Press
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More information
Scope and Contents
Contents
Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle. In this prospective study, involving 260 abacavir-naive individuals (7.7% of whom were positive for HLA-B*5701), we confirm the usefulness of genetic risk stratif...
Alternative Titles
Full title
Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_journals_219977313
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_219977313
Other Identifiers
ISSN
1058-4838
E-ISSN
1537-6591
DOI
10.1086/504874