Cohesin disrupts polycomb-dependent chromosome interactions
Cohesin disrupts polycomb-dependent chromosome interactions
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
How chromosome organisation is related to genome function remains poorly understood. Cohesin, loop-extrusion, and CTCF have been proposed to create structures called topologically associating domains (TADs) to regulate gene expression. Here, we examine chromosome conformation in embryonic stem cells lacking cohesin and find as in other cell types t...
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Cohesin disrupts polycomb-dependent chromosome interactions
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TN_cdi_proquest_journals_2200088929
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2200088929
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E-ISSN
2692-8205
DOI
10.1101/593970
How to access this item
https://www.proquest.com/docview/2200088929?pq-origsite=primo&accountid=13902
