The antifibrogenic effect of (−)-epigallocatechin gallate results from the induction of de novo synt...
The antifibrogenic effect of (−)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells
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New York: Elsevier Inc
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English
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New York: Elsevier Inc
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Hepatic stellate cells (HSC) are the major players during hepatic fibrogenesis. Overproduction of extracellular matrix (ECM) is a characteristic of activated HSC. Transforming growth factor-beta (TGF-β) is the most potent fibrogenic cytokine while connective tissue growth factor (CTGF) mediates the production of TGF-β-induced ECM in activated HSC....
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Full title
The antifibrogenic effect of (−)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells
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TN_cdi_proquest_journals_220274565
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_220274565
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/labinvest.3700425
