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The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA

The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2202945985

The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA

About this item

Full title

The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The double-helical structure of DNA results from canonical base pairing and stacking interactions. However, variations from steady-state conformations result from mechanical perturbations in cells. These different topologies have physiological relevance but their dependence on sequence remains unclear. Here, we use molecular dynamics simulations to...

Alternative Titles

Full title

The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2202945985

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2202945985

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/599480