A parallel cell-cycle entry pathway with inverted G1 signaling and alternate point of no return
A parallel cell-cycle entry pathway with inverted G1 signaling and alternate point of no return
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Cell-cycle entry relies on an orderly progression of signaling events. To start, cells first activate the kinase cyclin D-CDK4/6, which leads to eventual inactivation of the retinoblastoma protein Rb. Hours later, cells inactivate APC/CCDH1 and cross the final commitment point. However, many cells with genetically deleted cyclin Ds, which activate...
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Full title
A parallel cell-cycle entry pathway with inverted G1 signaling and alternate point of no return
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TN_cdi_proquest_journals_2202948278
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2202948278
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E-ISSN
2692-8205
DOI
10.1101/600007
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https://www.proquest.com/docview/2202948278?pq-origsite=primo&accountid=13902
