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Single-molecule analysis reveals the rapid effect of estradiol on the surface movement of AMPAR in l...

Single-molecule analysis reveals the rapid effect of estradiol on the surface movement of AMPAR in l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2205738117

Single-molecule analysis reveals the rapid effect of estradiol on the surface movement of AMPAR in live neurons

About this item

Full title

Single-molecule analysis reveals the rapid effect of estradiol on the surface movement of AMPAR in live neurons

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The gonadal steroid 17β-estradiol (E2) rapidly alters glutamatergic neurotransmission, but its direct effect on the AMPA receptor (AMPAR) remains unknown. Live-cell single-molecule imaging experiments revealed that E2 rapidly and dose-dependently alters the surface movement of AMPAR via membrane estrogen receptors with distinct effects on somas and...

Alternative Titles

Full title

Single-molecule analysis reveals the rapid effect of estradiol on the surface movement of AMPAR in live neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2205738117

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2205738117

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/602813