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Jagged1 Ablation Results in Cerebellar Granule Cell Migration Defects and Depletion of Bergmann Glia

Jagged1 Ablation Results in Cerebellar Granule Cell Mig...

Jagged1 Ablation Results in Cerebellar Granule Cell Migration Defects and Depletion of Bergmann Glia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_221141552

Jagged1 Ablation Results in Cerebellar Granule Cell Migration Defects and Depletion of Bergmann Glia

About this item

Full title

Jagged1 Ablation Results in Cerebellar Granule Cell Migration Defects and Depletion of Bergmann Glia

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Developmental neuroscience, 2006-01, Vol.28 (1-2), p.70-80

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Jagged1 is a ligand for members of the Notch family of receptors. Mutations in the human JAG1 gene are the major cause of Alagille syndrome, an autosomal dominant disorder affecting the liver, heart, eye, skeleton, kidneys, and craniofacial structures. Although expressed throughout mammalian embryonic development and in the adult, the function of J...

Alternative Titles

Full title

Jagged1 Ablation Results in Cerebellar Granule Cell Migration Defects and Depletion of Bergmann Glia

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_221141552

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_221141552

Other Identifiers

ISBN

9783805580861,380558086X

ISSN

0378-5866

E-ISSN

1421-9859

DOI

10.1159/000090754

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