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2,3′,4,4′,5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway

2,3′,4,4′,5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2213647674

2,3′,4,4′,5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway

About this item

Full title

2,3′,4,4′,5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of toxicology, 2019-06, Vol.93 (6), p.1639-1648

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

2,3′,4,4′,5-Pentachlorobiphenyl (PCB118) has been shown to cause thyroidal ultrastructure lesions, but the underlying mechanism remains elusive. This study aimed to elucidate the mechanism by which PCB118 induces the abnormalities of the thyrocytes. Wistar rats were injected intraperitoneally with PCB118 (0, 10, 100 and 1000 μg/kg/d) for 13 weeks,...

Alternative Titles

Full title

2,3′,4,4′,5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2213647674

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2213647674

Other Identifiers

ISSN

0340-5761

E-ISSN

1432-0738

DOI

10.1007/s00204-019-02458-x

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