FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression
FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression
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Author / Creator
FeiFei, Wang , HongHai, Xu , YongRong, Yan , PingXiang, Wu , JianHua, Wu , XiaoHui, Zhu , JiaoYing, Li , JingBo, Sun , Kun, Zhou , XiaoLi, Ren , Lu, Qi , XiaoLiang, Lan , ZhiQiang, Cheng , Na, Tang , WenTing, Liao , YanQing, Ding and Li, Liang
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
F-box only protein 8 (FBX8), as a critical component of the SKP1-CUL1-F-box (SCF) E3 ubiquitin ligases, has been associated with several malignancies through interacting with a member of proteins. However, the substrates of FBX8 for destruction in the progression of colorectal carcinoma (CRC) need to be explored. Here, we show that loss of FBX8 acc...
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Full title
FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression
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TN_cdi_proquest_journals_2214988218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2214988218
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-019-1588-z
