IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent ac...
IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis
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Liang, Mengmeng , Ma, Qinyu , Ding, Ning , Luo, Fei , Bai, Yun , Kang, Fei , Gong, Xiaoshan , Dong, Rui , Dai, Jingjin , Dai, Qijie , Dou, Ce and Dong, Shiwu
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
A variety of osteolytic factors have been identified from breast cancer cells leading to osteolysis, but less is known about which factor plays an essential role in the initiation process prior to the overt vicious osteolytic cycle. Here, we present in vitro and in vivo evidences to clarify the role of interleukin-11 (IL-11) as an essential contrib...
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IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis
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TN_cdi_proquest_journals_2217459934
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2217459934
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-019-1594-1