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IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent ac...

IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent ac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2217459934

IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis

About this item

Full title

IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2019-04, Vol.10 (5), p.353-353, Article 353

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A variety of osteolytic factors have been identified from breast cancer cells leading to osteolysis, but less is known about which factor plays an essential role in the initiation process prior to the overt vicious osteolytic cycle. Here, we present in vitro and in vivo evidences to clarify the role of interleukin-11 (IL-11) as an essential contrib...

Alternative Titles

Full title

IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2217459934

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2217459934

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-019-1594-1

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