Screening human embryos for polygenic traits has limited utility
Screening human embryos for polygenic traits has limited utility
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Genome-wide association studies have led to the development of polygenic score (PS) predictors that explain increasing proportions of the variance in human complex traits. In parallel, progress in preimplantation genetic testing now allows genome-wide genotyping of embryos generated via in vitro fertilization (IVF). Jointly, these developments sugg...
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Screening human embryos for polygenic traits has limited utility
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TN_cdi_proquest_journals_2220080246
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2220080246
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E-ISSN
2692-8205
DOI
10.1101/626846
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https://www.proquest.com/docview/2220080246?pq-origsite=primo&accountid=13902