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Screening human embryos for polygenic traits has limited utility

Screening human embryos for polygenic traits has limited utility

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2220080246

Screening human embryos for polygenic traits has limited utility

About this item

Full title

Screening human embryos for polygenic traits has limited utility

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Genome-wide association studies have led to the development of polygenic score (PS) predictors that explain increasing proportions of the variance in human complex traits. In parallel, progress in preimplantation genetic testing now allows genome-wide genotyping of embryos generated via in vitro fertilization (IVF). Jointly, these developments sugg...

Alternative Titles

Full title

Screening human embryos for polygenic traits has limited utility

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2220080246

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2220080246

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/626846