Inhibition of host Lactate dehydrogenase A by a small-molecule limits Mycobacterium tuberculosis gro...
Inhibition of host Lactate dehydrogenase A by a small-molecule limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Lactate dehydrogenase A (LDHA) mediates interconversion of pyruvate and lactate. Increased lactate turnover is shared by malignant and immune cells. Hypoxic lung granuloma in Mycobacterium tuberculosis-infected animals present elevated levels of Ldha and lactate. Such alteration in metabolic milieu could influence the outcome of interactions betwee...
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Full title
Inhibition of host Lactate dehydrogenase A by a small-molecule limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid
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TN_cdi_proquest_journals_2221134016
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2221134016
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E-ISSN
2692-8205
DOI
10.1101/626002
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https://www.proquest.com/docview/2221134016?pq-origsite=primo&accountid=13902
