Pharmacokinetics and safety of a fully human hepatocyte growth factor antibody, AMG 102, in cynomolg...
Pharmacokinetics and safety of a fully human hepatocyte growth factor antibody, AMG 102, in cynomolgus monkeys
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Publisher
New York, NY: Springer
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Language
English
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Publisher
New York, NY: Springer
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Scope and Contents
Contents
AMG 102, a fully human monoclonal antibody that binds to hepatocyte growth factor (HGF), is a potential cancer therapeutic agent because of its ability to disrupt HGF/c-Met signaling pathways which have been implicated in most tumor types. To support a phase 1 study, the pharmacokinetic and safety profile of AMG 102 was assessed in cynomolgus monke...
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Full title
Pharmacokinetics and safety of a fully human hepatocyte growth factor antibody, AMG 102, in cynomolgus monkeys
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TN_cdi_proquest_journals_222666808
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_222666808
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-007-9316-2
