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The NK-1 Receptor Is Expressed in Human Primary Gastric and Colon Adenocarcinomas and Is Involved in...

The NK-1 Receptor Is Expressed in Human Primary Gastric and Colon Adenocarcinomas and Is Involved in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_222678814

The NK-1 Receptor Is Expressed in Human Primary Gastric and Colon Adenocarcinomas and Is Involved in the Antitumor Action of L-733,060 and the Mitogenic Action of Substance P on Human Gastrointestinal Cancer Cell Lines

About this item

Full title

The NK-1 Receptor Is Expressed in Human Primary Gastric and Colon Adenocarcinomas and Is Involved in the Antitumor Action of L-733,060 and the Mitogenic Action of Substance P on Human Gastrointestinal Cancer Cell Lines

Publisher

Basel, Switzerland: Springer Nature B.V

Journal title

Tumor biology, 2008-01, Vol.29 (4), p.245-254

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: Springer Nature B.V

More information

Scope and Contents

Contents

Background/Aims: It has been demonstrated that substance P (SP) and neurokinin-1 (NK-1) receptor antagonist L-733,060 induces cell proliferation and inhibition, respectively, in several human cancer cell lines. At present, it is unknown whether such actions are exerted on human gastric and colon adenocarcinomas. We carried out an in vitro study of...

Alternative Titles

Full title

The NK-1 Receptor Is Expressed in Human Primary Gastric and Colon Adenocarcinomas and Is Involved in the Antitumor Action of L-733,060 and the Mitogenic Action of Substance P on Human Gastrointestinal Cancer Cell Lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_222678814

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_222678814

Other Identifiers

ISSN

1010-4283

E-ISSN

1423-0380

DOI

10.1159/000152942

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