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Hepatic damage in biliary-obstructed rats is ameliorated by leflunomide treatment

Hepatic damage in biliary-obstructed rats is ameliorated by leflunomide treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_222704275

Hepatic damage in biliary-obstructed rats is ameliorated by leflunomide treatment

About this item

Full title

Hepatic damage in biliary-obstructed rats is ameliorated by leflunomide treatment

Publisher

Germany: Springer Nature B.V

Journal title

Pediatric surgery international, 2006-09, Vol.22 (9), p.701-708

Language

English

Formats

Publication information

Publisher

Germany: Springer Nature B.V

More information

Scope and Contents

Contents

Cholestasis, or impaired bile flow, occurs in a wide variety of liver diseases and causes hepatic damage by retention and accumulation of toxic hydrophobic bile salts inducing persistent inflammation and oxidative stress. In the present research, we studied the effect of leflunomide, a novel immunosuppressive and anti-inflammatory agent against aut...

Alternative Titles

Full title

Hepatic damage in biliary-obstructed rats is ameliorated by leflunomide treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_222704275

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_222704275

Other Identifiers

ISSN

0179-0358

E-ISSN

1437-9813

DOI

10.1007/s00383-006-1744-2

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