Prosurvival autophagy is regulated by protein kinase CK1 alpha in multiple myeloma
Prosurvival autophagy is regulated by protein kinase CK1 alpha in multiple myeloma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Multiple myeloma (MM) is a tumor of plasma cells (PCs). Due to the intense immunoglobulin secretion, PCs are prone to endoplasmic reticulum stress and activate several stress-managing pathways, including autophagy. Indeed, autophagy deregulation is maladaptive for MM cells, resulting in cell death. CK1α, a pro-survival kinase in MM, has recently be...
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Full title
Prosurvival autophagy is regulated by protein kinase CK1 alpha in multiple myeloma
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TN_cdi_proquest_journals_2228653192
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2228653192
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ISSN
2058-7716
E-ISSN
2058-7716
DOI
10.1038/s41420-019-0179-1
