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Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_223115182

Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

About this item

Full title

Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2003-06, Vol.9 (6), p.762-767

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

In monkeys rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), expression of the dopamine D
3
receptor was decreased. However, levodopa-induced dyskinesia (LID), similar to the debilitating and pharmacoresistant involuntary movements elicited after long-term treatment with levodopa in patients with Parkinson diseas...

Alternative Titles

Full title

Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_223115182

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_223115182

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm875

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