The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testin...
The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing
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Publisher
New York: Springer US
Journal title
Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Erythromycin is an antibiotic that prolongs the QT-interval and causes Torsade de Pointes (TdP) by blocking the rapid delayed rectifying potassium current (
I
Kr
) without affecting either the slow delayed rectifying potassium current (
I
Ks
) or inward rectifying potassium current (
I
K1
). Erythromycin exerts this effec...
Alternative Titles
Full title
The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing
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TN_cdi_proquest_journals_2235406098
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2235406098
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ISSN
1530-7905
E-ISSN
1559-0259
DOI
10.1007/s12012-019-09532-x