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Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marr...

Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2235412429

Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment

About this item

Full title

Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Bone marrow (BM) mesenchymal stem cells (MSCs) are critical components of the BM microenvironment and play an essential role in supporting hematopoiesis. Dysfunction of MSCs is associated with the impaired BM microenvironment that promotes leukemia development. However, whether and how restoration of the impaired BM microenvironment can inhibit leu...

Alternative Titles

Full title

Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2235412429

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2235412429

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/661298