Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer
Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer
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Author / Creator
Van Cutsem, Eric , Köhne, Claus-Henning , Hitre, Erika , Zaluski, Jerzy , Chang Chien, Chung-Rong , Makhson, Anatoly , D'Haens, Geert , Pintér, Tamás , Lim, Robert , Bodoky, György , Roh, Jae Kyung , Folprecht, Gunnar , Ruff, Paul , Stroh, Christopher , Tejpar, Sabine , Schlichting, Michael , Nippgen, Johannes and Rougier, Philippe
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
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Publisher
United States: Massachusetts Medical Society
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Scope and Contents
Contents
Previous trials have shown that the combination of fluorouracil-based chemotherapy and cetuximab is active when used as salvage treatment in patients with metastatic colorectal cancer; the present trial shows activity of this combination as first-line treatment as well. The trial also found that for cetuximab to be active, an unmutated
KRAS
g...
Alternative Titles
Full title
Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer
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Record Identifier
TN_cdi_proquest_journals_223912188
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_223912188
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0805019
