A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery
A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery
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Author / Creator
Fergusson, Dean A , Hébert, Paul C , Mazer, C. David , Fremes, Stephen , MacAdams, Charles , Murkin, John M , Teoh, Kevin , Duke, Peter C , Arellano, Ramiro , Blajchman, Morris A , Bussières, Jean S , Côté, Dany , Karski, Jacek , Martineau, Raymond , Robblee, James A , Rodger, Marc , Wells, George , Clinch, Jennifer , Pretorius, Roanda and BART Investigators
Publisher
Boston, MA: Massachusetts Medical Society
Journal title
Language
English
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Publisher
Boston, MA: Massachusetts Medical Society
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Scope and Contents
Contents
In this clinical trial involving patients undergoing high-risk cardiac surgery, aprotinin was somewhat more effective than either aminocaproic acid or tranexamic acid in reducing massive perioperative bleeding but at the expense of a higher rate of death, mainly from cardiac causes. Aprotinin cannot be recommended to control blood loss in this clin...
Alternative Titles
Full title
A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery
Authors, Artists and Contributors
Author / Creator
Hébert, Paul C
Mazer, C. David
Fremes, Stephen
MacAdams, Charles
Murkin, John M
Teoh, Kevin
Duke, Peter C
Arellano, Ramiro
Blajchman, Morris A
Bussières, Jean S
Côté, Dany
Karski, Jacek
Martineau, Raymond
Robblee, James A
Rodger, Marc
Wells, George
Clinch, Jennifer
Pretorius, Roanda
BART Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_223922169
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_223922169
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0802395
