A Placebo-Controlled Trial of Prucalopride for Severe Chronic Constipation
A Placebo-Controlled Trial of Prucalopride for Severe Chronic Constipation
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Author / Creator
Publisher
Boston, MA: Massachusetts Medical Society
Journal title
Language
English
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Publisher
Boston, MA: Massachusetts Medical Society
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Scope and Contents
Contents
In this 12-week randomized trial, prucalopride, a selective 5-HT
4
receptor agonist, substantially relieved constipation. Because of cardiac adverse events seen with other 5-HT
4
receptor agonists, electrocardiograms were monitored; there was no prolongation of the corrected QT interval. Diarrhea and headache were more common in the pru...
Alternative Titles
Full title
A Placebo-Controlled Trial of Prucalopride for Severe Chronic Constipation
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TN_cdi_proquest_journals_223924980
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_223924980
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ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0800670