Everolimus Retards Cyst Growth and Preserves Kidney Function in a Rodent Model for Polycystic Kidney...
Everolimus Retards Cyst Growth and Preserves Kidney Function in a Rodent Model for Polycystic Kidney Disease
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Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Contents
Background/Aims: Rapamycin inhibits cyst growth in polycystic kidney disease by targeting the mammalian target of rapamycin (mTOR). To determine if this is a class effect of the mTOR inhibitors, we examined the effect of everolimus, the analogue of rapamycin, on disease progression in the Han:SPRD rat model of polycystic kidney disease. Methods: Fo...
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Full title
Everolimus Retards Cyst Growth and Preserves Kidney Function in a Rodent Model for Polycystic Kidney Disease
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TN_cdi_proquest_journals_224119192
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_224119192
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ISSN
1420-4096
E-ISSN
1423-0143
DOI
10.1159/000104818
