Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction...
Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction factor
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Author / Creator
Liu, Ying , Fu, Yajing , Wang, Qian , Li, Mushan , Zhou, Zheng , Dabbagh, Deemah , Fu, Chunyan , Zhang, Hang , Li, Shuo , Zhang, Tengjiang , Gong, Jing , Kong, Xiaohui , Zhai, Weiwei , Su, Jiaming , Sun, Jianping , Zhang, Yonghong , Yu, Xiao-Fang , Shao, Zhen , Zhou, Feng , Wu, Yuntao and Tan, Xu
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Human immunodeficiency virus (HIV) actively modulates the protein stability of host cells to optimize viral replication. To systematically examine this modulation in HIV infection, we used isobaric tag-based mass spectrometry to quantify changes in the abundance of over 14,000 proteins during HIV-1 infection of human primary CD4
+
T cells. We...
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Full title
Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction factor
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TN_cdi_proquest_journals_2242109430
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2242109430
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ISSN
2058-5276
E-ISSN
2058-5276
DOI
10.1038/s41564-019-0372-2
