An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo
An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo
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Washington: National Academy of Sciences
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English
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Washington: National Academy of Sciences
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Myeloperoxidase (MPO) is a critical proinflammatory enzyme implicated in cardiovascular, neurological, and rheumatological diseases. Emerging therapies targeting inflammation have raised interest in tracking MPO activity in patients. We describe 18F-MAPP, an activatable MPO activity radioprobe for positron emission tomography (PET) imaging. The act...
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An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo
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TN_cdi_proquest_journals_2245650135
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2245650135
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1901987116