Fluorine-modified sialyl-Tn-CRM197 vaccine elicits a robust immune response
Fluorine-modified sialyl-Tn-CRM197 vaccine elicits a robust immune response
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Author / Creator
Song, Chengcheng , Zheng, Xiu-Jing , Guo, Haili , Cao, Yafei , Zhang, Fan , Li, Qin , Ye, Xin-Shan and Zhou, Yifa
Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Even though a vaccine that targets tumor-associated carbohydrate antigens on epithelial carcinoma cells presents an attractive therapeutic approach, relatively poor immunogenicity limits its development. In this study, we investigated the immunological activity of a fluoro-substituted Sialyl-Tn (F-STn) analogue coupled to the non-toxic cross-reacti...
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Full title
Fluorine-modified sialyl-Tn-CRM197 vaccine elicits a robust immune response
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Record Identifier
TN_cdi_proquest_journals_2250836925
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2250836925
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ISSN
0282-0080
E-ISSN
1573-4986
DOI
10.1007/s10719-019-09884-0