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Virtual screening identifies novel high-affinity σ1 receptor ligands

Virtual screening identifies novel high-affinity σ1 receptor ligands

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2255970631

Virtual screening identifies novel high-affinity σ1 receptor ligands

About this item

Full title

Virtual screening identifies novel high-affinity σ1 receptor ligands

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-07

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The σ1 receptor is a transmembrane protein implicated in several pathophysiological conditions, including neurodegenerative disease, drug addiction, cancer, and pain. However, there are no high-throughput functional assays for σ1 receptor drug discovery. Here, we assessed high-throughput structure-based computational docking for discovery of novel...

Alternative Titles

Full title

Virtual screening identifies novel high-affinity σ1 receptor ligands

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2255970631

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2255970631

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/699793