An antibody-tumor necrosis factor fusion protein that synergizes with oxaliplatin for treatment of c...
An antibody-tumor necrosis factor fusion protein that synergizes with oxaliplatin for treatment of colorectal cancer
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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We have cloned and characterized a novel fusion protein (Sm3E-TNF), consisting of the monoclonal antibody Sm3E in single-chain Fv fragment format, fused to murine tumor necrosis factor. The protein, which was expressed in mammalian cells and purified as a non-covalent stable homotrimer, bound to the cognate carcinoembryonic antigen (CEA) and retain...
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Full title
An antibody-tumor necrosis factor fusion protein that synergizes with oxaliplatin for treatment of colorectal cancer
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TN_cdi_proquest_journals_2259096180
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2259096180
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E-ISSN
2692-8205
DOI
10.1101/698563
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https://www.proquest.com/docview/2259096180?pq-origsite=primo&accountid=13902
