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SC79, a novel Akt activator, protects dopaminergic neuronal cells from MPP+ and rotenone

SC79, a novel Akt activator, protects dopaminergic neuronal cells from MPP+ and rotenone

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2263015494

SC79, a novel Akt activator, protects dopaminergic neuronal cells from MPP+ and rotenone

About this item

Full title

SC79, a novel Akt activator, protects dopaminergic neuronal cells from MPP+ and rotenone

Publisher

New York: Springer US

Journal title

Molecular and cellular biochemistry, 2019-11, Vol.461 (1-2), p.81-89

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

In pathogenesis of Parkinson’s disease (PD), mitochondrial dysfunction causes substantial reactive oxygen species (ROS) production and oxidative stress, leading to dopaminergic (DA) neuronal cell death. Mitochondrial toxins, including MPP
+
(1-methyl-4-phenylpyridinium ion) and rotenone, induce oxidative injury in cultured DA neuronal cells....

Alternative Titles

Full title

SC79, a novel Akt activator, protects dopaminergic neuronal cells from MPP+ and rotenone

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2263015494

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2263015494

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-019-03592-x

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