A review of kallikrein inhibitor lanadelumab in hereditary angioedema
A review of kallikrein inhibitor lanadelumab in hereditary angioedema
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Publisher
London: Future Medicine Ltd
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Language
English
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Publisher
London: Future Medicine Ltd
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Contents
Hereditary angioedema with C1 esterase inhibitor deficiency is a rare disorder characterized by unpredictable swelling of the face, larynx and gastrointestinal tract. Kallikreins are serine proteases that cleave kininogens to produce bradykinin leading to inflammation. A new prophylactic drug is lanadelumab (DX-2930, SHP-643), a recombinant, fully...
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Full title
A review of kallikrein inhibitor lanadelumab in hereditary angioedema
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TN_cdi_proquest_journals_2276754145
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2276754145
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ISSN
1750-743X
E-ISSN
1750-7448
DOI
10.2217/imt-2018-0197