Structure of the antithrombin–thrombin–heparin ternary complex reveals the antithrombotic mechanism...
Structure of the antithrombin–thrombin–heparin ternary complex reveals the antithrombotic mechanism of heparin
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The maintenance of normal blood flow depends completely on the inhibition of thrombin by antithrombin, a member of the serpin family. Antithrombin circulates at a high concentration, but only becomes capable of efficient thrombin inhibition on interaction with heparin or related glycosaminoglycans. The anticoagulant properties of therapeutic hepari...
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Structure of the antithrombin–thrombin–heparin ternary complex reveals the antithrombotic mechanism of heparin
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TN_cdi_proquest_journals_228264490
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_228264490
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb811
