Peptide-triggered conformational switch in HIV-1 RRE RNA complexes
Peptide-triggered conformational switch in HIV-1 RRE RNA complexes
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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We have used NMR spectroscopy to determine the solution structure of a complex between an oligonucleotide derived from stem IIB of the Rev responsive element (RRE-IIB) of HIV-1 mRNA and an
in vivo
selected, high affinity binding Arg-rich peptide. The peptide binds in a partially α-helical conformation into a pocket within the RNA deep groove....
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Full title
Peptide-triggered conformational switch in HIV-1 RRE RNA complexes
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TN_cdi_proquest_journals_228305079
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_228305079
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ISSN
1072-8368,1545-9993
E-ISSN
1545-9985
DOI
10.1038/84138
