Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells...
Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Naive CD4+ T cells coordinate the immune response by acquiring an effector phenotype in response to cytokines. However, the cytokine responses in memory T cells remain largely understudied. We used quantitative proteomics, bulk RNA-seq and single-cell RNA-seq of over 40,000 human naive and memory CD4+ T cells to generate a detailed map of cytokine-...
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Full title
Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines
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TN_cdi_proquest_journals_2284295420
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2284295420
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E-ISSN
2692-8205
DOI
10.1101/753731
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https://www.proquest.com/docview/2284295420?pq-origsite=primo&accountid=13902
