Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert...
Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with TP 53 mutations
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Publisher
Frankfurt: EMBO Press
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Language
English
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Publisher
Frankfurt: EMBO Press
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Scope and Contents
Contents
Heterozygous inactivating mutations in ribosomal protein genes (RPGs) are associated with hematopoietic and developmental abnormalities, activation of p53, and altered risk of cancer in humans and model organisms. Here we performed a large‐scale analysis of cancer genome data to examine the frequency and selective pressure of RPG lesions across hum...
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Full title
Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with TP 53 mutations
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TN_cdi_proquest_journals_2290184944
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2290184944
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201606660
