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Synergistic induction of CCL 2/ MCP ‐1 expression driven by oncostatin M and IL ‐1 β in human proxim...

Synergistic induction of CCL 2/ MCP ‐1 expression driven by oncostatin M and IL ‐1 β in human proxim...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2290686747

Synergistic induction of CCL 2/ MCP ‐1 expression driven by oncostatin M and IL ‐1 β in human proximal tubular cells depends on STAT 3 and p65 NF κ B/RelA

About this item

Full title

Synergistic induction of CCL 2/ MCP ‐1 expression driven by oncostatin M and IL ‐1 β in human proximal tubular cells depends on STAT 3 and p65 NF κ B/RelA

Publisher

Oxford: John Wiley & Sons, Inc

Journal title

Physiological reports, 2015-02, Vol.3 (2)

Language

English

Formats

Publication information

Publisher

Oxford: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

In response to tubular injury, production, and secretion of cytokines, chemokines or extracellular matrix components by human proximal tubular epithelial cells (PTC) directly contribute to the development of tubulointerstitial inflammation and fibrosis. Here, we report a novel stimulatory and synergistic effect of oncostatin M (OSM) on proinflammat...

Alternative Titles

Full title

Synergistic induction of CCL 2/ MCP ‐1 expression driven by oncostatin M and IL ‐1 β in human proximal tubular cells depends on STAT 3 and p65 NF κ B/RelA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2290686747

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2290686747

Other Identifiers

E-ISSN

2051-817X

DOI

10.14814/phy2.12298

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